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PDE4D Antibody (MA5-50555) in WB
Western blot analysis of PDE4D in Hela cell lysates. Lysates/proteins at 10 µg/Lane. Predicted band size: 91 kDa. Observed band size: 91 kDa. Exposure time: 30 seconds; 6% SDS-PAGE gel. Primary antibody PDE4D monoclonal antibody (Product # MA5-50555) with a dilution of 1:500 was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Mouse IgG-HRP Secondary Antibody with a dilution of 1:100,000 was used for 1 hour at room temperature. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temp... View More
产品信息
MA5-50555
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
A7F3
抗原
Recombinant protein within Human PDE4D aa 610-809/809.
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.05% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3091327
产品详细信息
Positive control: Hela cell lysates.
Predicted band size: 91 kDa
Subcellular Location: Apical cell membrane, Cytoplasm, Cytoskeleton, Centrosome, Membrane.
靶标信息
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3',5'-cyclic-AMP phosphodiesterase 4D; cAMP-specific phosphodiesterase 4D; cAMP-specific phosphodiesterase PDE4D6; DKFZp686M11213; DPDE3; FLJ97311; HGNC:8783; HS PDE4DN2; PDE43; PDE4D3; PDE4D7; phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila); testicular tissue protein Li 136
基因别名: ACRDYS2; DPDE3; HSPDE4D; PDE43; PDE4D; PDE4DN2; STRK1
UniProt ID: (Human) Q08499
Entrez Gene ID: (Human) 5144
regulation of heart rate
cAMP catabolic process
smooth muscle contraction
aging
regulation of receptor activity
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
cAMP-mediated signaling
neutrophil chemotaxis
regulation of cAMP metabolic process
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of interleukin-5 production
negative regulation of peptidyl-serine phosphorylation
multicellular organism growth
negative regulation of heart contraction
T cell receptor signaling pathway
regulation of ryanodine-sensitive calcium-release channel activity
establishment of endothelial barrier
cellular response to lipopolysaccharide
cellular response to epinephrine stimulus
adrenergic receptor signaling pathway
regulation of cardiac muscle cell contraction
adrenergic receptor signaling pathway involved in positive regulation of heart rate
regulation of cell communication by electrical coupling involved in cardiac conduction
negative regulation of relaxation of cardiac muscle
