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产品信息
PA5-79799
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human PDK2 (379-392aa WRHYQTIQEAGDWC).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2746914
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial; PDH kinase 2; PDK P45; pyruvate dehydrogenase; pyruvate dehydrogenase 2; pyruvate dehydrogenase kinase 2 subunit p45 (PDK2); Pyruvate dehydrogenase kinase isoform 2; pyruvate dehydrogenase kinase, isoenzyme 2; pyruvate dehydrogenase kinase, isozyme 2; pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
基因别名: PDHK2; PDK2; PDKII
UniProt ID: (Human) Q15119, (Rat) Q64536
Entrez Gene ID: (Human) 5164, (Rat) 81530
glucose metabolic process
regulation of gluconeogenesis
protein phosphorylation
regulation of pH
insulin receptor signaling pathway
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of cellular ketone metabolic process
regulation of glucose metabolic process
cellular response to nutrient
cellular response to reactive oxygen species
glucose homeostasis
intrinsic apoptotic signaling pathway by p53 class mediator
peptidyl-serine phosphorylation
