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PDK2 Antibody (BSM-51043M) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Human Liver tissue; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 15 minutes; Blocking buffer (3% BSA) at room temperature for 30min; Antibody incubation with PDK2 (180CT10.2.3) Monoclonal Antibody (bsm-51043M) at 1:25 for 1 hour at 37°C, followed by a conjugated secondary antibody fo... View More
产品信息
BSM-51043M
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
7E5
抗原
This PDK2 monoclonal antibody is generated from mouse immunized with PDK2 recombinant protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
TBS, pH 7.4, with 1% BSA, 40% glycerol
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial; PDH kinase 2; pyruvate dehydrogenase; pyruvate dehydrogenase 2; Pyruvate dehydrogenase kinase isoform 2; pyruvate dehydrogenase kinase, isoenzyme 2; pyruvate dehydrogenase kinase, isozyme 2; pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
基因别名: PDHK2; PDK2; PDKII
UniProt ID: (Human) Q15119, (Mouse) Q9JK42
Entrez Gene ID: (Human) 5164, (Mouse) 18604
protein kinase activity
pyruvate dehydrogenase (acetyl-transferring) kinase activity
ATP binding
protein homodimerization activity
nucleotide binding
protein serine/threonine kinase activity
protein binding
kinase activity
transferase activity
protein complex binding
protein heterodimerization activity
non-receptor serine/threonine protein kinase
glucose metabolic process
regulation of gluconeogenesis
protein phosphorylation
regulation of pH
insulin receptor signaling pathway
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of cellular ketone metabolic process
regulation of glucose metabolic process
cellular response to nutrient
cellular response to reactive oxygen species
glucose homeostasis
intrinsic apoptotic signaling pathway by p53 class mediator
carbohydrate metabolic process
phosphorylation
peptidyl-serine phosphorylation
