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产品信息
PA5-28019
应用
建议稀释比
已发表文章
产品规格
种属反应
Amphibian,
Human,
Mouse,
Rodent
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 7 and 290 of Human PDK3
偶联物
形式
Liquid
浓度
0.16 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545495
产品详细信息
Recommended positive controls: HepG2, mouse liver, PDK3-transfected 293T.
Predicted reactivity: Mouse (96%), Rat (96%), Chicken (93%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial; pyruvate dehydrogenase; pyruvate dehydrogenase kinase 3; Pyruvate dehydrogenase kinase isoform 3; pyruvate dehydrogenase kinase, isoenzyme 3; pyruvate dehydrogenase kinase, isozyme 3; pyruvate dehydrogenase, lipoamide, kinase isozyme 3, mitochondrial
基因别名: 2610001M10Rik; AI035637; CMTX6; GS1-358P8.4; PDHK3; PDK3
UniProt ID: (Human) Q15120, (Mouse) Q922H2
Entrez Gene ID: (Human) 5165, (Mouse) 236900
glucose metabolic process
regulation of acetyl-CoA biosynthetic process from pyruvate
regulation of glucose metabolic process
peptidyl-serine phosphorylation
peroxisome proliferator activated receptor signaling pathway
cellular response to glucose stimulus
cellular response to fatty acid
hypoxia-inducible factor-1alpha signaling pathway
regulation of reactive oxygen species metabolic process
carbohydrate metabolic process
phosphorylation
