Search Thermo Fisher Scientific
Positive Control: Mouse testis
Predicted Reactivity: Human (100%), Rat (97%), Xenopus laevis (80%), Chicken (85%), Bovine (98%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PDP1 is a Pyruvate dehydrogenase and helps catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; FLJ32517; FLJ56179; MGC119646; PDP 1; PDPC 1; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; Pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 2
基因别名: Gm1024; PDH; PDP; PDP1; PDPC; PPM2A; PPM2C
UniProt ID: (Human) Q9P0J1, (Mouse) Q3UV70
Entrez Gene ID: (Human) 54704, (Mouse) 381511
分子生物学功能: protein phosphatase