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PEA15 Antibody (MA5-47429) in IHC (PFA)
Immunohistochemistry analysis of PEA15 in rat brain section. Samples were stained with PEA15 monoclonal antibody (Product # MA5-47429) using a dilution of 1:1,000 (red). Costained with chicken pAb to MAP2 dilution 1:5,000 in green. The blue is Hoechst staining of nuclear DNA. Following transcardial perfusion of rat with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45 μM, and free-floating ... View More
产品信息
MA5-47429
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
4D117
抗原
Full length human PEA-15 as expressed in and purified from E. coli.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS with 50% glycerol
内含物
5mM sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2942411
靶标信息
PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 15 kDa phosphoprotein enriched in astrocytes; Astrocytic phosphoprotein PEA-15; homolog of mouse MAT-1 oncogene; mammary transforming gene 1; mammary transforming gene 1, mouse, homolog of; OTTHUMP00000029887; PED; phosphoprotein enriched in astrocytes 15; phosphoprotein enriched in astrocytes 15A; Phosphoprotein enriched in diabetes
基因别名: HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PEA15; Pea15a; PED; Pkcs15
UniProt ID: (Human) Q15121, (Rat) Q5U318, (Mouse) Q62048
Entrez Gene ID: (Human) 8682, (Bovine) 510586, (Rat) 364052, (Mouse) 18611
DNA damage checkpoint
MAPK cascade
activation of MAPK activity
transport
apoptotic process
carbohydrate transport
response to morphine
negative regulation of glucose import
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
intracellular signal transduction
regulation of apoptotic process
