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PEG3 Antibody (PA5-116550) in IHC (P)
Immunohistochemistry analysis of PEG3 in paraffin-embedded mouse brain. Samples were incubated with PEG3 Polyclonal antibody (Product # PA5-116550) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-116550
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 195-400 of human PEG3 (NP_0062011)
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901181
产品详细信息
Positive Samples: HepG2
Immunogen sequence: LSLPVVAKTS FEMDREDDRD SRAYESRSQD AESYQNVVDL AEDRKPHNTI QDNMENYRKL LSLVQLAEDD GHSHMTQGHS SRSKRSAYPS TSRGLKTMPE AKKSTHRRGI CEDESSHGVI MEKFIKDVSR SSKSGRARES SDRSQRFPRM SDDNWKDISL NKRESVIQQR VYEGNAFRGG FRFNSTLVSR KRVLERKRRY HFDTDG
靶标信息
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASF-1; granule cell antiserum positive 4; Kruppel-type zinc finger protein; paternally expressed gene 3; Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24
基因别名: AL022617; ASF-1; End4; Gcap4; KIAA0287; mKIAA0287; PEG3; PW1; Zfp102; ZKSCAN22; ZNF904; ZSCAN24
UniProt ID: (Human) Q9GZU2, (Mouse) Q3URU2
Entrez Gene ID: (Human) 5178, (Mouse) 18616
