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This antibody detects endogenous protein at a molecular weight of 42 kDa.
Purity is >95% by SDS-PAGE.
Peroxin 3, also known as PEX3 (peroxisomal biogenesis factor 3) or TRG18, is a 373 amino acid multi-pass membrane protein that localizes to peroxisomes and belongs to the Peroxin family. Expressed ubiquitously, Peroxin 3 interacts with Peroxin 19 and is involved in peroxisome biosynthesis and membrane vesicle assembly, as well as in the maintenance of peroxisomal integrity. Additionally, Peroxin 3 acts as a docking factor for Peroxin 19 and is required for the import of peroxisomal proteins. Defects in the gene encoding Peroxin 3 are the cause of peroxisome biogenesis disorder complementation group 12 (PBD-CG12) and Zellweger syndrome (ZwS), both of which arise from a failure of peroxisomal protein import.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Peroxin-3; Peroxin3; peroxisomal assembly protein 3; Peroxisomal assembly protein PEX3; Peroxisomal biogenesis factor 3; transformation-related protein 18
基因别名: 1700014F15Rik; 2810027F19Rik; 2900010N04Rik; PBD10A; PEX3; TRG18
UniProt ID: (Human) P56589, (Mouse) Q9QXY9, (Rat) Q9JJK4
Entrez Gene ID: (Human) 8504, (Mouse) 56535, (Rat) 83519