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Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). PGAM2 encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; PGAM-M; Phosphoglycerate mutase 2; phosphoglycerate mutase 2 (muscle); Phosphoglycerate mutase isozyme M; phosphoglycerate mutase muscle-specific subunit
基因别名: GSD10; PGAM-M; PGAM2; PGAMM
UniProt ID: (Human) P15259, (Mouse) O70250
Entrez Gene ID: (Human) 5224, (Mouse) 56012