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The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 25-DX; Acidic 25 kDa protein; Dap1; HGNC:16090; IZA; Membrane-associated progesterone receptor component 1; membrane-bound progesterone receptor; mPR; progesterone binding protein; steroid membrane binding protein; VEMA; Ventral midline antigen
基因别名: 25-Dx; 25Dx; AA415812; HPR6.6; Lewi; MPR; PGRMC; PGRMC1; PPMR; VEMA
UniProt ID: (Pig) Q95250, (Human) O00264, (Rat) P70580, (Mouse) O55022
Entrez Gene ID: (Pig) 396946, (Human) 10857, (Rat) 291948, (Mouse) 53328