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Immunogen sequence: IKRGVLKEI YDKDGELSIS NEEDSLENGQ SLSSSQLSLP ALSEMEPVPM PRDPCSYEVL QPSDIMDGPD PGAPVKLPCL PVKLSPPLPP KKVMICMPVG GPDLSLVSYT AQKSGQQGVA QHHHTVLPSQ IQHQLQYGSH GQHLPSTTGS LPMHPSGCRM IDELNKTLAM TMQRLESSEQ RVPCSTSYHS SGLHSGDGVT KAGPMGLPEI RQVPTVVIEC DDNKENVPHE SDYEDSSCLY TREEEEEEED EDDDSSLYTS SLAMKVCRKD SLAI (154-426 aa encoded by B C101526)
PHACTR1 plays a role in cell motility and in the formation of tubules by endothelial cells. PHACTR1 also binds actin monomers (G actin) and plays a role in the reorganization of the actin cytoskeleton and in formation of actin stress fibers. Further, PHACTR1 regulates PPP1CA activity and is required for normal cell survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC126575; MGC126577; Phosphatase and actin regulator 1; RPEL repeat containing 1
基因别名: 9630030F18Rik; dJ257A7.2; KIAA1733; PHACTR1; RPEL; RPEL1
UniProt ID: (Human) Q9C0D0, (Rat) P62024, (Mouse) Q2M3X8
Entrez Gene ID: (Human) 221692, (Rat) 306844, (Mouse) 218194