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Immunogen sequence: QTVKSHTET DEKQTESRTI TPPAAPKPKR EENPQKLAFM VSLGLVTHDH LEEIQSKRQE RKRRTTANPV YSGAVFEPER KKSAVTYLNS TMHPGTRKRG RPPKYNAVLG FGALTPTSPQ SSHPDSPENE KTETTFTFPA PVQPVSLPSP TSTDGDIHED FCSVCRKSGQ LLMCDTCSRV YHLDCLDPPL KTIPKGMWIC PRCQDQMLKK EEAIPWPGTL AIVHSYIAYK AAKEEEKQKL LKWSSDLKQE REQLEQKVKQ LSNSISKCME MKNTILARQK EMHSSLEKVK QLIRLIHGID LSKPVDSEAT VGAISNGPDC TPPANAATST PAPSPSSQSC TANCNQGEET K (331-680 aa encoded by BC015714)
PHF21A (PHD finger protein 21A) is a component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, PHF21A may act as a scaffold.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BHC80a; BRAF35-HDAC complex protein BHC80; Braf35/HDAC complex (Bhc); BRAF35/HDAC2 complex; BRAF35/HDAC2 complex (80 kDa); mBHC80; PHD finger protein 21A
基因别名: 80kDa; Bhc; BHC80; BM-006; D030065N23Rik; KIAA1696; PFTF1; PHF21A; RGD1560612
UniProt ID: (Human) Q9C0G7, (Mouse) Q6ZPK0
Entrez Gene ID: (Human) 51317, (Rat) 362166, (Mouse) 192285