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Immunogen sequence: PKEMTKWNSN DFIDAFASPV EAEGTPEPGA EAAKGIEDGA QAPRDSEGLD GAGELGAEAC AVHALFLILH SGNILDSGP
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 81%.
Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Drosophila retinal degeneration B homolog; FLJ44997; Membrane-associated phosphatidylinositol transfer protein 1; NIR-2; phosphatidylinositol transfer protein, membrane associated 1; Phosphatidylinositol transfer protein, membrane-associated 1; PITPnm 1; PYK2 N-terminal domain-interacting receptor 2; retinal degeneration B alpha 1
基因别名: DRES9; NIR2; PITPNM; PITPNM1; Rd9; RDGB; RDGB1; RDGBA; RDGBA1
UniProt ID: (Human) O00562
Entrez Gene ID: (Human) 9600
分子生物学功能:
transporter