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Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MRPDDKYHEK QAQVEATKLK QKVEALSPGD RQQIYEKGLE LRSQQSKPQD ASCLPALKVS DIEPTIPVTE LDVVLTAGDI PVQYCAQPTN GMVYFRAFSS LNTLPEELRP YVPLFCSVLT KLGCGLLDYR EQAQQIELKT GGMSASPHVL PDDSHMDTYE QGVLFSSLCL DRNLPDMMQL WSEIFNNPCF EEEEHFKVLV KMTAQELANG IPDSGHLYAS IRAGRTLTPA GDLQETFSGM DQVRLMKRIA EMTDIKPILR KLPRIKKHLL NGDNMRCSVN ATPQQMPQTE KAVEDFLRSI GRSKKERRPV RPHTVEKPVP SSSGGDAHVP HGSQVIRKLV MEPTFKPWQM KTHFLMPFPV NYVGECIRTV PYTDPDHASL KILARLMTAK FLHTEIREKG GAYGGGAKLS HNGIFTLYSY RDPNTIETLQ SFGKAVDWAK SGKFTQQDID EAKLSVFSTV DAPVAPSDKG MDHFLYGLSD EMKQAHREQL FAVSHDKLLA VSDRYLGTGK STHGLAILGP ENPKIAKDPS WIIR
The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hPreP; Metalloprotease 1; metalloprotease 1 (pitrilysin family); Pitrilysin metalloproteinase 1; PreP peptidasome; Presequence protease, mitochondrial
基因别名: KIAA1104; MP1; PITRM1; PREP
UniProt ID: (Human) Q5JRX3
Entrez Gene ID: (Human) 10531