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Recommended positive controls: U87-MG.
Predicted reactivity: Mouse (92%), Rat (94%), Zebrafish (86%), Pig (98%), Chicken (92%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A MGC138466; Autosomal dominant polycystic kidney disease type II protein; MGC138468; PC2; polycystic kidney disease 2 (autosomal dominant); Polycystic kidney disease 2 protein; Polycystin-2; Polycystwin; R48321; Transient receptor potential cation channel subfamily P member 2; transient receptor potential cation channel, subfamily P, member 2; TRPP1
基因别名: APKD2; Pc-2; PC2; PKD2; PKD4; TRPP2
UniProt ID: (Human) Q13563
Entrez Gene ID: (Human) 5311
分子生物学功能:
ion channel