Invitrogen

PKP3 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他8个PKP3抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

高级验证 (1)

图: 1 / 1

PKP3 Antibody (PA5-84574)

Relative expression in different tissues in IHC: Detection of differential expression levels of PKP3 demonstrates antibody specificity. Immunohistochemical analysis of PKP3 using anti-PKP3 Polyclonal Antibody (Product #PA5-84574), shows significant staining of PKP3 in skin and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of PKP3 within each tissue is shown using... View More

Product Image Gallery

PKP3 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of PKP3 demonstrates antibody specificity. Immunohistochemical analysis of PKP3 using anti-PKP3 Polyclonal Antibody (Product #PA5-84574), shows significant staining of PKP3 in skin and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of PKP3 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-84574

应用

建议稀释比

已发表文章

免疫组化 (IHC)

1:20-1:50

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PKP3. Recombinant protein control fragment (Product #RP-104169).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Anitgen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2791725

产品详细信息

Immunogen sequence: FDDIDLPSAV KYLMASDPNL QVLGAAYIQH KCYSDAAAKK QARSLQAVPR LVKLFNHANQ EVQRHATGAM RNLI

靶标信息

Plakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.

仅用于科研。不用于诊断过程。未经明确授权不得转售。