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产品信息
PA5-90209
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 875-1036 of human PLD1 (NP_0011235531)
偶联物
形式
Liquid
浓度
1.57 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805961
产品详细信息
Immunogen sequence: NINDRSMLGK RDSEMAVIVQ DTETVPSVMD GKEYQAGRFA RGLRLQCFRV VLGYLDDPSE DIQDPVSDKF FKEVWVSTAA RNATIYDKVF RCLPNDEVHN LIQLRDFINK PVLAKEDPIR AEEELKKIRG FLVQFPFYFL SEESLLPSVG TKEAIVPMEV WT; Positive Samples: HeLa, HT-29, LO2; Cellular Location: Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Golgi apparatus membrane, Late endosome membrane, Lipid-anchor, perinuclear region
靶标信息
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Choline phosphatase 1; hPLD1; phophatidylcholine-specific; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1
基因别名: PLD1
UniProt ID: (Human) Q13393
Entrez Gene ID: (Human) 5337
