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Antibody detects endogenous levels of total Plexin D1.
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC75353; Plexin-D1
基因别名: KIAA0620; PLEXD1; PLXND1
UniProt ID: (Human) Q9Y4D7
Entrez Gene ID: (Human) 23129