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Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein which is a member of the claudin family and is thought to play an important role in the structure of peripheral nerve myelin. Irregularities in its gene results in hereditary demyelinating neuropathies. PMP22 protein is present in the compact myelin of adult human peripheral nerve and its distribution mimics that of Myelin Protein zero (P0).
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蛋白别名: GAS-3; Growth arrest-specific protein 3; peripheral myelin; Peripheral myelin protein 22; peripheral myelin protein 22 kDa; PMP-22; Protein CD25; SAG; Schwann cell membrane glycoprotein; SR13 myelin protein
基因别名: 22kDa; Cd25; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Pmp-22; PMP22; Sp110; Tr; trembler
UniProt ID: (Human) Q01453, (Rat) P25094, (Mouse) P16646
Entrez Gene ID: (Human) 5376, (Rat) 24660, (Mouse) 18858