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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein which is a member of the claudin family and is thought to play an important role in the structure of peripheral nerve myelin. Irregularities in its gene results in hereditary demyelinating neuropathies. PMP22 protein is present in the compact myelin of adult human peripheral nerve and its distribution mimics that of Myelin Protein zero (P0).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GAS-3; Growth arrest-specific protein 3; peripheral myelin; Peripheral myelin protein 22; peripheral myelin protein 22 kDa; PMP-22
基因别名: 22kDa; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Pmp-22; PMP22; Sp110; Tr; trembler
UniProt ID: (Human) Q01453, (Mouse) P16646
Entrez Gene ID: (Human) 5376, (Mouse) 18858
分子生物学功能:
cytoskeletal protein