Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA5-25530
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI1D2
抗原
Full length human recombinant protein of PNMT produced in HEK293T cell
偶联物
Unconjugated
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723492
靶标信息
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Noradrenaline N-methyltransferase; phenylethanolamine N-methylase; Phenylethanolamine N-methyltransferase; PNMTase
基因别名: PENT; PNMT; PNMTase
UniProt ID: (Human) P11086, (Mouse) P40935, (Rat) P10937
Entrez Gene ID: (Human) 5409, (Dog) 491023, (Mouse) 18948, (Rat) 24661
methylation
epinephrine biosynthetic process
catecholamine biosynthetic process
norepinephrine metabolic process
response to hypoxia
response to cold
response to water deprivation
response to activity
adrenal gland development
response to corticosteroid
response to insulin
social behavior
response to isolation stress
response to immobilization stress
response to peptide hormone
response to ethanol
response to ether
S-adenosylhomocysteine metabolic process
S-adenosylmethionine metabolic process
sensory perception of taste
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to dexamethasone stimulus
