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MA5-15589 targets PPP1A in indirect ELISA, WB applications and shows reactivity with Human and mouse samples.
The MA5-15589 immunogen is purified recombinant fragment of human PPP1A expressed in E. Coli.
MA5-15589 detects PPP1A which has a predicted molecular weight of approximately 38kDa.
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GADD34; MGC15877; MGC1674; PP-1A; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155
基因别名: dism2; PP-1A; PP1A; PP1alpha; PPP1A; Ppp1c; PPP1CA
UniProt ID: (Human) P62136, (Mouse) P62137
Entrez Gene ID: (Human) 5499, (Mouse) 19045