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PP2A alpha/beta Antibody (PA5-78119) in IHC (P)
PP2A alpha/beta Polyclonal Antibody detects PP2A alpha + PP2A beta protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. PP2A alpha + PP2A beta stained by PP2A alpha/beta Polyclonal Antibody (Product # PA5-78119) diluted at 1:1,000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-78119
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PP2A alpha. The exact sequence is proprietary.
偶联物
Unconjugated
形式
Liquid
浓度
1.11 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2736451
产品详细信息
Positive Control: 293T, A431, HeLa, HepG2
Predicted Reactivity: Zebrafish (100%), Pig (100%), Rabbit (100%), Bovine (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PP2A-alpha; PP2A-beta; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, alpha isozyme; protein phosphatase 2, catalytic subunit, beta isoform; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2A catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; Replication protein C; RP C; RP-C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; testicular tissue protein Li 146
基因别名: PP2Abeta; PP2Ac; PP2CA; PP2Calpha; PP2CB; PPP2CA; PPP2CB; RP-C
UniProt ID: (Human) P67775, (Human) P62714
Entrez Gene ID: (Human) 5515, (Human) 5516
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
inactivation of MAPK activity
regulation of DNA replication
regulation of transcription, DNA-templated
protein dephosphorylation
ceramide metabolic process
apoptotic process
mitotic nuclear envelope reassembly
mesoderm development
RNA splicing
response to organic substance
negative regulation of epithelial to mesenchymal transition
second-messenger-mediated signaling
regulation of Wnt signaling pathway
regulation of cell adhesion
negative regulation of cell growth
regulation of growth
negative regulation of tyrosine phosphorylation of Stat3 protein
regulation of cell differentiation
meiotic cell cycle
positive regulation of protein serine/threonine kinase activity
apoptotic mitochondrial changes
regulation of gene expression
response to endoplasmic reticulum stress
response to hydrogen peroxide
proteasome-mediated ubiquitin-dependent protein catabolic process
response to antibiotic
