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产品信息
PA5-60302
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2645802
产品详细信息
Immunogen sequence: RWEMDRGRGR LCDQKFPKTK DKSQGAQARR GPRGASRDGG
Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 38%.
靶标信息
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
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生物信息学
蛋白别名: Brix domain-containing protein 3; homolog of S. cerevisiae SSF1; Peter Pan homolog; second-step splicing factor 1; Ssf-1; suppressor of sterile four 1; Suppressor of SWI4 1 homolog
基因别名: BXDC3; PPAN; SSF; SSF-1; SSF1; SSF2
UniProt ID: (Human) Q9NQ55
Entrez Gene ID: (Human) 56342
