Invitrogen

PPAR gamma Monoclonal Antibody (C5)

查看其他18个PPAR gamma抗体

抗体检测数据 (5)

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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PPAR gamma Antibody (MA5-41659) in IHC (P)

Immunohistochemistry analysis of PPAR-gamma in paraffin-embedded Rat Stomach tissue. Samples were incubated with monoclonal antibody (Product # MA5-41659) at a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 2 µg/mL.

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P))

PPAR gamma Antibody in Western Blot (WB)

PPAR gamma Antibody in Western Blot (WB)

Product Image Gallery

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of PPAR-gamma in paraffin-embedded Rat Stomach tissue. Samples were incubated with monoclonal antibody (Product # MA5-41659) at a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 2 µg/mL.

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of PPAR-gamma in paraffin-embedded Rat Testis tissue. Samples were incubated with monoclonal antibody (Product # MA5-41659) at a dilution of 30 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 2 µg/mL.

PPAR gamma Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of PPAR-gamma in paraffin-embedded Rat Heart tissue. Samples were incubated with monoclonal antibody (Product # MA5-41659) at a dilution of 30 µg/mL.

PPAR gamma Antibody in Western Blot (WB) — Western blot analysis of PPAR-gamma in Lane 1: Porcine Cerebrum lysate; Lane 2: Rat Liver lysate; Lane 3: K562 cell lysate. Samples were incubated with monoclonal antibody (Product # MA5-41659) at a dilution of 5 µg/mL, followed by HRP-Linked Caprine Anti-Mouse IgG using a dilution of 0.2 µg/mL.

PPAR gamma Antibody in Western Blot (WB) — Western blot analysis of PPAR-gamma in recombinant rat PPARg. Sample was incubated with monoclonal antibody (Product # MA5-41659).

产品信息

MA5-41659

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.01-2 µg/mL

-

免疫组化（石蜡） (IHC (P))

5-30µg/mL

-

产品规格

种属反应

Rat

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

C5

抗原

Recombinant protein Peroxisome Proliferator Activated Receptor Gamma. The antigen corresponds to amino acid range 311-493 of the target protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2899141

靶标信息

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: HUMPPARG; Nuclear receptor subfamily 1 group C member 3; OTTHUMP00000185032; OTTHUMP00000185036; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor gamma; peroxisome proliferator activator receptor, gamma; Peroxisome proliferator-activated receptor gamma; PPAR gamma; PPAR-gamma; PPARy

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基因别名: Nr1c3; Pparg

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UniProt ID: (Rat) O88275

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Entrez Gene ID: (Rat) 25664

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RNA polymerase II regulatory region DNA binding core promoter sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding protein binding transcription factor binding drug binding zinc ion binding enzyme binding protein phosphatase binding estrogen receptor binding ligand-dependent nuclear receptor transcription coactivator activity activating transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding retinoid X receptor binding arachidonic acid binding alpha-actinin binding C4 zinc finger nuclear receptor DNA-binding transcription factor zinc finger transcription factor gene-specific transcriptional regulator

参与通路

negative regulation of transcription from RNA polymerase II promoter negative regulation of cytokine production placenta development negative regulation of acute inflammatory response transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter fatty acid metabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process signal transduction heart development regulation of blood pressure negative regulation of cell proliferation response to cold response to light stimulus response to mechanical stimulus response to organic substance negative regulation of macrophage derived foam cell differentiation negative regulation of receptor biosynthetic process negative regulation of cholesterol storage negative regulation of sequestering of triglyceride response to organic cyclic compound long-chain fatty acid transport regulation of lipid metabolic process fatty acid oxidation monocyte differentiation negative regulation of cell growth epithelial cell differentiation response to caffeine organ regeneration response to food response to retinoic acid cellular response to insulin stimulus negative regulation of collagen biosynthetic process response to vitamin A response to lipid peroxisome proliferator activated receptor signaling pathway response to immobilization stress response to diuretic response to drug glucose homeostasis response to starvation regulation of circadian rhythm lipoprotein transport positive regulation of apoptotic process steroid hormone mediated signaling pathway response to estrogen cell fate commitment fat cell differentiation regulation of fat cell differentiation positive regulation of fat cell differentiation low-density lipoprotein particle receptor biosynthetic process negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of fatty acid oxidation cell maturation rhythmic process negative regulation of smooth muscle cell proliferation positive regulation of oligodendrocyte differentiation white fat cell differentiation brown fat cell differentiation positive regulation of sequence-specific DNA binding transcription factor activity negative regulation of telomerase activity response to low-density lipoprotein particle positive regulation of phagocytosis, engulfment negative regulation of interferon-gamma-mediated signaling pathway regulation of transcription involved in cell fate commitment cellular response to lithium ion cellular response to retinoic acid cellular response to vitamin E cellular response to prostaglandin stimulus cellular response to prostaglandin E stimulus cellular response to organic cyclic compound cellular response to hyperoxia negative regulation of peptide hormone secretion negative regulation of cellular response to insulin stimulus response to metformin negative regulation of pancreatic stellate cell proliferation