Product References
EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang J,Qiu H,Huang J,Ding S,Huang B,Zhou P,Jiang Q
Tue Jan 01 00:00:00 EST 2019
Chronic treatment with the modified Longdan Xiegan Tang attenuates olanzapine-induced fatty liver in rats by regulating hepatic de novo lipogenesis and fatty acid beta-oxidation-associated gene expression mediated by SREBP-1c, PPAR-alpha and AMPK-alpha.
Journal of ethnopharmacology
Ren L,Sun D,Zhou X,Yang Y,Huang X,Li Y,Wang C,Li Y
Mon Mar 25 00:00:00 EDT 2019
Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.
British journal of pharmacology
Ma C,Zhang W,Yang X,Liu Y,Liu L,Feng K,Zhang X,Yang S,Sun L,Yu M,Yang J,Li X,Hu W,Miao RQ,Zhu Y,Li L,Han J,Chen Y,Duan Y
Tue May 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
Life sciences
Zhou Y,Du D,Liu S,Zhao M,Yuan Y,Li L,Chen Y,Lu Y,Cheng J,Liu J
Sun Jul 01 00:00:00 EDT 2018
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity.
Life sciences
Zhou Y,Du D,Liu S,Zhao M,Yuan Y,Li L,Chen Y,Lu Y,Cheng J,Liu J
Sun Jul 01 00:00:00 EDT 2018
Isoquercitrin Attenuated Cardiac Dysfunction Via AMPKα-Dependent Pathways in LPS-Treated Mice.
Molecular nutrition & food research
Huang SH,Xu M,Wu HM,Wan CX,Wang HB,Wu QQ,Liao HH,Deng W,Tang QZ
Sat Dec 01 00:00:00 EST 2018
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
PPAR research
Wang W,Chen K,Xia Y,Mo W,Wang F,Dai W,Niu P
Thu Mar 31 00:00:00 EDT 2022
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation.
PPAR research
Wang W,Chen K,Xia Y,Mo W,Wang F,Dai W,Niu P
Thu Mar 31 00:00:00 EDT 2022
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
Biochemical and biophysical research communications
Zhang J,Qiu H,Huang J,Ding S,Huang B,Wu Q,Jiang Q
Sat Jul 07 00:00:00 EDT 2018
Effects of mulberry leaf on experimental hyperlipidemia rats induced by high-fat diet.
Experimental and therapeutic medicine
Huang J,Wang Y,Ying C,Liu L,Lou Z
Wed Aug 01 00:00:00 EDT 2018
Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease.
NPJ systems biology and applications
Maldonado EM,Fisher CP,Mazzatti DJ,Barber AL,Tindall MJ,Plant NJ,Kierzek AM,Moore JB
Wed Nov 20 00:00:00 EST 2019
Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake.
EBioMedicine
Xiao Y,Yan W,Lu Y,Zhou K,Cai W
Sat Sep 01 00:00:00 EDT 2018
Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake.
EBioMedicine
Xiao Y,Yan W,Lu Y,Zhou K,Cai W
Sat Sep 01 00:00:00 EDT 2018
Cholesterol-lowering effects and potential mechanisms of chitooligosaccharide capsules in hyperlipidemic rats.
Food & nutrition research
Jiang Y,Fu C,Liu G,Guo J,Su Z
Fri Mar 18 00:00:00 EDT 2022
GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis.
PloS one
Wang C,Li L,Liu S,Liao G,Li L,Chen Y,Cheng J,Lu Y,Liu J
Mon Jun 25 00:00:00 EDT 2018
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a.
Neuropharmacology
Ji J,Zeng XN,Cao LL,Zhang L,Zhao Z,Yang DD,Sun XL
Wed Feb 01 00:00:00 EST 2017
miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells.
RNA biology
Chen Z,Luo J,Sun S,Cao D,Shi H,Loor JJ
Sat Mar 04 00:00:00 EST 2017
The effects of di 2-ethyl hexyl phthalate (DEHP) on cellular lipid accumulation in HepG2 cells and its potential mechanisms in the molecular level.
Toxicology mechanisms and methods
Zhang W,Shen XY,Zhang WW,Chen H,Xu WP,Wei W
Mon May 01 00:00:00 EDT 2017
The effects of di 2-ethyl hexyl phthalate (DEHP) on cellular lipid accumulation in HepG2 cells and its potential mechanisms in the molecular level.
Toxicology mechanisms and methods
Zhang W,Shen XY,Zhang WW,Chen H,Xu WP,Wei W
Mon May 01 00:00:00 EDT 2017
Dietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice.
Oncotarget
Hu J,Luo H,Jiang Y,Chen P
Tue Jun 13 00:00:00 EDT 2017
Metabolomics reveal mitochondrial and fatty acid metabolism disorders that contribute to the development of DKD in T2DM patients.
Molecular bioSystems
Li L,Wang C,Yang H,Liu S,Lu Y,Fu P,Liu J
Tue Oct 24 00:00:00 EDT 2017
Nutritional background changes the hypolipidemic effects of fenofibrate in Nile tilapia (Oreochromis niloticus).
Scientific reports
Ning LJ,He AY,Lu DL,Li JM,Qiao F,Li DL,Zhang ML,Chen LQ,Du ZY
Tue Jan 31 00:00:00 EST 2017
Di(2-ethylhexyl) phthalate exacerbates non-alcoholic fatty liver in rats and its potential mechanisms.
Environmental toxicology and pharmacology
Chen H,Zhang W,Rui BB,Yang SM,Xu WP,Wei W
Tue Mar 01 00:00:00 EST 2016
Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice.
Chemico-biological interactions
Han X,Li W,Huang D,Yang X
Sun Sep 25 00:00:00 EDT 2016
Jatrorrhizine hydrochloride attenuates hyperlipidemia in a high-fat diet-induced obesity mouse model.
Molecular medicine reports
Yang W,She L,Yu K,Yan S,Zhang X,Tian X,Ma S,Zhang X
Sat Oct 01 00:00:00 EDT 2016
Mechanisms and metabolic regulation of PPARα activation in Nile tilapia (Oreochromis niloticus).
Biochimica et biophysica acta
Ning LJ,He AY,Li JM,Lu DL,Jiao JG,Li LY,Li DL,Zhang ML,Chen LQ,Du ZY
Thu Sep 01 00:00:00 EDT 2016
Long noncoding RNA HULC modulates abnormal lipid metabolism in hepatoma cells through an miR-9-mediated RXRA signaling pathway.
Cancer research
Cui M,Xiao Z,Wang Y,Zheng M,Song T,Cai X,Sun B,Ye L,Zhang X
Sun Mar 01 00:00:00 EST 2015
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Chronobiology international
Wang D,Chen S,Liu M,Liu C
Mon Jun 01 00:00:00 EDT 2015
Protective effects of heparin on endothelial cells in sepsis.
International journal of clinical and experimental medicine
Ma J,Bai J
Wed Jul 01 00:00:00 EDT 2015
Potent effects of dioscin against obesity in mice.
Scientific reports
Liu M,Xu L,Yin L,Qi Y,Xu Y,Han X,Zhao Y,Sun H,Yao J,Lin Y,Liu K,Peng J
Thu Jan 22 00:00:00 EST 2015
I prostanoid receptor-mediated inflammatory pathway promotes hepatic gluconeogenesis through activation of PKA and inhibition of AKT.
Diabetes
Yan S,Zhang Q,Zhong X,Tang J,Wang Y,Yu J,Zhou Y,Zhang J,Guo F,Liu Y,FitzGerald GA,Yu Y
Mon Sep 01 00:00:00 EDT 2014
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Food & function
Dong D,Qi Y,Xu L,Yin L,Xu Y,Han X,Zhao Y,Peng J
Mon Dec 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
Protective effects of dioscin against alcohol-induced liver injury.
Archives of toxicology
Xu T,Zheng L,Xu L,Yin L,Qi Y,Xu Y,Han X,Peng J
Sat Mar 01 00:00:00 EST 2014
Lipoic acid entrains the hepatic circadian clock and lipid metabolic proteins that have been desynchronized with advanced age.
Biochemical and biophysical research communications
Keith D,Finlay L,Butler J,Gómez L,Smith E,Moreau R,Hagen T
Fri Jul 18 00:00:00 EDT 2014
Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats.
Food chemistry
Zhang S,Zheng L,Dong D,Xu L,Yin L,Qi Y,Han X,Lin Y,Liu K,Peng J
Sun Dec 01 00:00:00 EST 2013
Dihydrocapsaicin Attenuates Plaque Formation through a PPARγ/LXRα Pathway in apoE(-/-) Mice Fed a High-Fat/High-Cholesterol Diet.
PloS one
Hu YW,Ma X,Huang JL,Mao XR,Yang JY,Zhao JY,Li SF,Qiu YR,Yang J,Zheng L,Wang Q
Thu Oct 12 00:00:00 EDT 2017