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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: fibroblast growth factor inducible 13; Fibroblast growth factor-inducible protein 13; FIN13; PP2C, gamma; PP2C-gamma; Protein phosphatase 1C; Protein phosphatase 1G; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 2C gamma isoform; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; protein phosphatase, Mg2+/Mn2+ dependent, 1G
基因别名: AI385652; Fin13; PP2CG; PP2CGAMMA; PPM1C; PPM1G; PPP2CG
UniProt ID: (Human) O15355, (Mouse) Q61074
Entrez Gene ID: (Human) 5496, (Mouse) 14208, (Rat) 259229