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产品信息
H00005532-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
5D3
抗原
PPP3CB (NP_066955, 435 a.a. approximately 524 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: LTPTGMLPSG VLAGGRQTLQ SATVEAIEAE KAIRGFSPPH RICSFEEAKG LDRINERMPP RKDAVQQDGF NSLNTAHATE NHGTGNHTAQ
靶标信息
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcineurin A beta; calcineurin A2; Calmodulin-dependent calcineurin A subunit beta isoform; CAM-PRP catalytic subunit; CNA beta; protein phosphatase 2B, catalytic subunit, beta isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform; protein phosphatase 3, catalytic subunit, beta isozyme; protein phosphatase from PCR fragment H32; RP11-345K20.1; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
基因别名: CALNA2; CALNB; CNA2; PP2Bbeta; PPP3CB
UniProt ID: (Human) P16298
Entrez Gene ID: (Human) 5532
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
signal transduction
Wnt signaling pathway, calcium modulating pathway
heart development
learning
memory
dephosphorylation
calcium ion regulated exocytosis
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
social behavior
cellular response to drug
positive regulation of insulin secretion involved in cellular response to glucose stimulus
Fc-epsilon receptor signaling pathway
T cell proliferation
T cell activation
T cell homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
axon extension
regulation of insulin secretion
positive regulation of NFAT protein import into nucleus
