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产品信息
TA500585
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Human,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2E12
抗原
Full length human recombinant protein of human PPP5C produced in HEK293T cell.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ36922; FLJ55954; OTTHUMP00000165834; PP-T; PP5; PPT; protein phosphatase 5, catalytic subunit; Protein phosphatase T; Serine/threonine-protein phosphatase 5
基因别名: PP5; PPP5; PPP5C; PPT
UniProt ID: (Human) P53041, (Rat) P53042
Entrez Gene ID: (Dog) 612199, (Human) 5536, (Rat) 65179
G-protein alpha-subunit binding
RNA binding
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
signal transducer activity
protein binding
ATP binding
microtubule binding
lipid binding
heat shock protein binding
identical protein binding
ADP binding
metal ion binding
protein phosphatase
MAPK cascade
negative regulation of protein phosphorylation
DNA repair
transcription, DNA-templated
protein dephosphorylation
mitotic nuclear division
response to lead ion
histone dephosphorylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to morphine
protein heterooligomerization
cellular response to hydrogen peroxide
cellular response to cadmium ion
negative regulation of neuron death
positive regulation of glucocorticoid receptor signaling pathway
signal transduction
dephosphorylation
protein oligomerization
negative regulation of cell death
