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产品信息
PA5-143124
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-HNVRTQEPTQQ.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2933763
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
靶标信息
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369). May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AGP7; azurophil granule protein 7; C-ANCA antigen; Leukocyte proteinase 3; Myeloblastin; Neutrophil proteinase 4; NP-4; P29; PR-3; serine proteinase, neutrophil; Wegener autoantigen; Wegener granulomatosis autoantigen
基因别名: ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3; PRTN3
UniProt ID: (Human) P24158
Entrez Gene ID: (Human) 5657
