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Positive test controls include: Mouse lung, Rat heart.
Immunogen sequence: LDLQHNRLSD GVFKPDTFHG LKNLMQLNLA HNILRKMPPR VPTAIHQLYL DSNKIETIPN GYFKSFPNLA FIRLNYNKLT DRGLPKNSFN ISNLLVLHLS HNRISSVPAI NNRLEHLYLN NNSIEKINGT QICPNDLVAF HDFSSDLENV PHLRYLRLDG N
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Prolargin; Proline-arginine-rich end leucine-rich repeat protein
基因别名: 7330409J17Rik; Prelp; SLRR2A
UniProt ID: (Mouse) Q9JK53, (Rat) Q9EQP5
Entrez Gene ID: (Mouse) 116847, (Rat) 84400