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Invitrogen
PRICKLE1 Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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PRICKLE1 Antibody (PA5-51570) in IHC
eLife 2020 -
Figure 5. FOXC1 and FOXC2 mediate lymphatic expression of the PCP signaling component and RHOA signaling regulator Prickle1. ( a ) Reduced expression of Prickle1 , Arhgap21 , and Arhgap23 in Foxc1/c2 -compound mutant LECs isolated from the dorsal skin at E15.5. Graph shows RPKM values from RNA-seq analysis. *** denotes p<0.001. ( b, c ) Putative FOX-binding sites in regions of the human PRICKLE1 locus as vi... View More
产品信息
PA5-51570
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human PRICKLE1
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2645937
产品详细信息
Immunogen sequence: GASGYNHDET QWYEDSLECL SDLKPEQSVR DSMDSLALSN ITGASVDGEN KPRPSLYSLQ NFEEMETEDC EKMSNMGTLN SSMLHRSAES LKSLSSELCP EKILPEEKPV HLPVLRRSKS QSRPQQVKFS DDVIDNGNYD IEI
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 94%.
靶标信息
Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
