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产品信息
CF500559
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI5E9
抗原
Full-length protein expressed in 293T cell transfected with human PRKY expression vector
偶联物
Unconjugated
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
A group of proteins that are intimately involved in this process are the serine/ threonine (Ser/Thr) protein kinases. PRKY (protein kinase, Y-linked) and PRKX (protein kinase, X-linked) are members of the Ser/Thr protein kinase family, both of which belong to the subfamily of cAMP-dependent kinases. Encoded by a gene that is located near the pseudoautosomal region on chromosome Y, PRKY contains one protein kinase domain through which it catalyzes the ATP-dependent phosphorylation of target proteins. Functioning in a similar manner to PRXY, PRKX contains one protein kinase domain and is essential for macrophage differentiation and renal epithelial cell migration. Defects in the genes encoding PRKY and PRXX are associated with sex reversal disorder, namely XX in males and XY in females.
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生物信息学
基因别名: PRKXP3; PRKYP
Entrez Gene ID: (Human) 5616
