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Immunogen sequence: VGRSDSVSTRL SNCDPPPTYE EATGQVNLQR SETEPHLDPP PEYEDIVNSN SASA
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 96%.
This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: proline rich Gla (G-carboxyglutamic acid) 1; Proline-rich gamma-carboxyglutamic acid protein 1; proline-rich Gla (G-carboxyglutamic acid) polypeptide 1; Proline-rich Gla protein 1; Transmembrane gamma-carboxyglutamic acid protein 1
基因别名: PRGP1; PRRG1; TMG1
UniProt ID: (Human) O14668
Entrez Gene ID: (Human) 5638
分子生物学功能:
serine protease