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PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 7S nerve growth factor gamma chain; 7S nerve growth factor gamma subunit; Antigen; Gamma-NGF; Glandular kallikrein K3; Kallikrein 1-related peptidase b3; Kallikrein 3; Kallikrein-1; Kallikrein-3 (KLK3); KLK-3; mGK-3; Nerve growth factor gamma chain; nerve growth factor gamma polypeptide; nerve growth factor, gamma; Pancreatic kallikrein; prostate-specific (APS); PS kallikrein; RGK-1; rK-1; Tissue kallikrein; Tissue kallikrein-3; True kallikrein; True tissue kallikrein
基因别名: Klk-1; Klk-3; Klk1; Klk1b3; Klk1c1; Klk3; mGk-3; Ngfg; rGK-1; rK-1
UniProt ID: (Rat) P00758, (Mouse) A2RTW1
Entrez Gene ID: (Rat) 24594, (Mouse) 18050