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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human PSG1/PS-beta-G-1.
Human pregnancy-specific glycoproteins (PSG), are a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD66 antigen-like family member F; CD66f; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; FLJ90598; FLJ90654; pregnancy-specific B-1 glycoprotein; Pregnancy-specific beta-1 glycoprotein C/D; Pregnancy-specific beta-1-glycoprotein 1; PS-beta-C/D; PS-beta-G-1; PSG 1; PSG IIA-d; PSG-1d; PSG95; PSGIIA-a; PSGIIA-b; PSGIIA-c; SP 1
基因别名: B1G1; CD66f; DHFRP2; FL-NCA-1/2; PBG1; PS-beta-C/D; PS-beta-G-1; PSBG-1; PSBG1; PSG1; PSG95; PSGGA; PSGIIA; SP1
UniProt ID: (Human) P11464
Entrez Gene ID: (Human) 5669