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This target displays homology in the following species: Human: 100%
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: carcinoembryonic antigen SG8; Pregnancy-specific beta-1 glycoprotein E; Pregnancy-specific beta-1-glycoprotein 2; pregnancy-specific beta-1-glycoprotein 7; pregnancy-specific beta-1-glycoprotein-2; pregnancy-specific glycoprotein 2; PS-beta-E; PS-beta-G-2; PSBG-2
基因别名: CEA; PSBG2; PSG1; PSG2
UniProt ID: (Human) P11465
Entrez Gene ID: (Human) 5670