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MA5-15615 targets PTH in WB applications and shows reactivity with Human samples.
The MA5-15615 immunogen is purified recombinant fragment of human PTH(aa1-115) expressed in E. Coli.
MA5-15615 detects PTH which has a predicted molecular weight of approximately 12.9kDa.
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness.
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