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PTPN7 Antibody (PA5-14559) in IHC (P)
Immunohistochemistry analysis of PTPN7 in formalin-fixed and paraffin-embedded human hepatocarcinoma tissue. Samples were incubated with PTPN7 polyclonal antibody (Product # PA5-14559) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
产品信息
PA5-14559
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 22-51 amino acids from human PTPN7
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10977803
靶标信息
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dual specificity phosphatase 1; Hematopoietic protein-tyrosine phosphatase; HEPTP; Protein-tyrosine phosphatase LC-PTP; protein-tyrosine phosphatase, nonreceptor-type, stress induced; Tyrosine-protein phosphatase non-receptor type 7
基因别名: BPTP-4; HEPTP; LC-PTP; LPTP; PTPN7; PTPNI
UniProt ID: (Human) P35236
Entrez Gene ID: (Human) 5778
