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This antibody is specific to PYGB. It has no cross reaction to PYGM and PYGL.
The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: brain glycogen phosphorylase; glycogen phosphorylase B; Glycogen phosphorylase, brain form; MGC9213
基因别名: GLYPHOA; GPBB; PYGB
UniProt ID: (Human) P11216, (Mouse) Q8CI94, (Rat) P53534
Entrez Gene ID: (Human) 5834, (Mouse) 110078, (Rat) 25739
分子生物学功能:
glycosyltransferase
transferase
metabolite interconversion enzyme