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PYGM Antibody (CF811295) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PYGM (RC212365, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PYGM. (1. Positive lysates LY401719 (100 µg) and LC401719 (20 µg) can be purchased separately from OriGene.
产品信息
CF811295
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI3C11
抗原
Human recombinant protein fragment corresponding to amino acids 698-842 of human PYGM produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: glycogen muscle; Glycogen phosphorylase, muscle form; GPMM; muscle (McArdle syndrome); muscle glycogen phosphorylase; Myophosphorylase; Phosphorylase glycogen; Phosphorylase, glycogen; muscle (McArdle syndrome)
基因别名: AI115133; Muscpho; PG; PYGM
UniProt ID: (Human) P11217, (Mouse) Q9WUB3
Entrez Gene ID: (Human) 5837, (Rat) 24701, (Mouse) 19309
protein binding
drug binding
glycogen phosphorylase activity
AMP binding
pyridoxal phosphate binding
carbohydrate binding
protein homodimerization activity
nucleotide binding
catalytic activity
phosphorylase activity
transferase activity
transferase activity, transferring glycosyl groups
glycosyltransferase
transferase
metabolite interconversion enzyme
