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7TM Antibodies
Phospho-Cannabinoid Receptor 1 (Ser429) Polyclonal Antibody
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Phospho-Cannabinoid Receptor 1 (Ser429) Antibody (7TM0056B) in WB
Agonist-induced Serine429 phosphorylation of the Cannabinoid Receptor 1. Upper panel, HEK293 cells stably expressing the CB1-Receptor (CB1) were either not exposed or exposed to 10 µM of CB1-Receptor Agonists CP55940 for 30 minutes. Cells were lysed and immunoblotted with the anti-pS429-CB1 antibody (7TM0056B) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with an phosphorylation-inde... View More
产品信息
7TM0056B
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic phosphopeptide derived from human CB1 around the phosphorylation site of Ser429.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
Dulbecco's PBS, pH 7.4
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB-R; CB1 receptor; central cannabinoid receptor; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1
基因别名: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; CNR1
UniProt ID: (Human) P21554
Entrez Gene ID: (Human) 1268
positive regulation of acute inflammatory response to antigenic stimulus
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
spermatogenesis
axonal fasciculation
aging
response to nutrient
memory
positive regulation of neuron projection development
sensory perception of pain
positive regulation of fever generation
negative regulation of fatty acid beta-oxidation
regulation of synaptic transmission, GABAergic
response to lipopolysaccharide
negative regulation of mast cell activation
negative regulation of dopamine secretion
response to nicotine
cannabinoid signaling pathway
response to cocaine
glucose homeostasis
positive regulation of apoptotic process
negative regulation of ion transport
response to morphine
response to ethanol
negative regulation of action potential
negative regulation of blood pressure
positive regulation of blood pressure
regulation of insulin secretion
negative regulation of nitric-oxide synthase activity
regulation of synaptic transmission, glutamatergic
maternal process involved in female pregnancy
regulation of feeding behavior
regulation of penile erection
