Invitrogen

Phospho-Caveolin 2 (Ser23) Polyclonal Antibody

Phospho-Caveolin 2 (Ser23) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Phospho-Caveolin 2 (Ser23) Antibody (PA5-118635) in IHC (P)

Immunohistochemical analysis of Phospho-Caveolin 2 (Ser23) in Mouse lung tissue using a Phospho-Caveolin 2 (Ser23) polyclonal antibody (Product # PA5-118635). The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as th... View More

Phospho-Caveolin 2 (Ser23) Antibody in Western Blot (WB)

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产品信息

PA5-118635

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse, Non-human primate, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human CAV2(Accession P51636), corresponding to amino acid residues around phosphorylated Ser23.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

RRID

AB_2903135

产品详细信息

Antibody detects endogenous levels of Caveolin 2 only when phosphorylated at Ser23.

靶标信息

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.

仅用于科研。不用于诊断过程。未经明确授权不得转售。