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Phospho-GKAP1 (Ser25) Antibody (PA5-105217) in IHC (P)
Immunohistochemistry analysis of Phospho-GKAP1 (Ser25) in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-GKAP1 (Ser25) polyclonal antibody (Product # PA5-105217) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-105217
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human GKAP1(Accession Q5VSY0), corresponding to amino acid residues around phosphorylated Ser25.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2816690
产品详细信息
Antibody detects endogenous levels of GKAP only when phosphorylated at Ser25.
靶标信息
The approximately 142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 42 kD cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein; cGMP-dependent protein kinase anchoring protein 42kDa; cGMP-dependent protein kinase-anchoring protein of 42 kDa; G kinase-anchoring protein 1; protein kinase anchoring protein GKAP42
基因别名: 42kDa; 4933400B15Rik; D13Ertd340e; FKSG21; GKAP1; GKAP42
UniProt ID: (Human) Q5VSY0, (Mouse) Q9JMB0, (Rat) Q5XIG5
Entrez Gene ID: (Human) 80318, (Mouse) 56278, (Rat) 361202
