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Antibody detects endogenous levels of HIPK1/2/3 only when phosphorylated at Tyr352/361/359.
The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Androgen receptor-interacting nuclear protein kinase; ANPK; Fas-interacting serine/threonine-protein kinase; FIST; HCMV-interacting protein; hHIPk2; hipk1 {ECO:0000312|EMBL:ABO47653.1}; homeodomain interacting protein kinase 1-like protein; Homeodomain-interacting protein kinase 1; Homeodomain-interacting protein kinase 2; Homeodomain-interacting protein kinase 3; Homolog of protein kinase YAK1; Nbak3; nuclear body associated kinase 2b; Nuclear body-associated kinase 1; Nuclear body-associated kinase 2; Nuclear body-associated kinase 3; nuclear serine/threonine protein kinase; Protein kinase Myak; Sialophorin tail-associated nuclear serine/threonine-protein kinase
基因别名: 1110014O20Rik; 1110062K04Rik; ANPK; B230339E18Rik; DYRK6; Fist; FIST3; HIPK1; HIPK2; HIPK3; KIAA0630; mir-1902; MYAK; Nbak1; NBAK2; PKY; PRO0593; Stank; YAK1
UniProt ID: (Human) Q86Z02, (Human) Q9H2X6, (Human) Q9H422, (Mouse) O88904, (Mouse) Q9QZR5, (Mouse) Q9ERH7, (Rat) O88850
Entrez Gene ID: (Human) 204851, (Human) 28996, (Human) 10114, (Rat) 365895, (Mouse) 15257, (Rat) 362342, (Mouse) 15258, (Mouse) 15259, (Rat) 83617