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产品信息
PA5-36659
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide derived from human JunB around the phosphorylation site of Serine 259
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553642
产品详细信息
This antibody detects endogenous protein at a molecular weight of 43 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
JunB, a member of the Jun cellular oncogene family, is a basic region, leucine zipper transcription factor. It is involved in regulating gene activity following the primary growth factor response. JunB binds to the DNA sequence 5'-TGA[CG]TCA-3'. Cellular oncogenes play critical roles in cellular communication pathways that regulate growth, development, and differentiation.
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生物信息学
蛋白别名: activator protein 1; Jun B; jun B proto-oncogene; Jun-B oncogene; MyD21; Oncogene Jun-B; Transcription factor AP-1 subunit JunB; transcription factor jun-B; Transcription factor JunB
基因别名: AP-1; Jun-b; JUNB
UniProt ID: (Human) P17275, (Rat) P24898, (Mouse) P09450
Entrez Gene ID: (Human) 3726, (Rat) 24517, (Mouse) 16477
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription coactivator activity
transcription corepressor activity
protein binding
transcription factor binding
RNA polymerase II regulatory region sequence-specific DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
protein heterodimerization activity
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
osteoblast differentiation
trophectodermal cell differentiation
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to radiation
response to light stimulus
response to mechanical stimulus
regulation of cell death
osteoclast differentiation
response to lipopolysaccharide
response to progesterone
cellular response to hormone stimulus
osteoblast proliferation
response to cytokine
regulation of cell proliferation
response to drug
response to peptide hormone
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
decidualization
response to corticosterone
response to cAMP
regulation of cell cycle
embryonic process involved in female pregnancy
labyrinthine layer blood vessel development
cellular response to calcium ion
in utero embryonic development
regulation of transcription, DNA-templated
female pregnancy
cellular process
response to organic cyclic compound
transcription, DNA-templated
