Search Thermo Fisher Scientific
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686I1536; MADS box transcription enhancer factor 2, polypeptide D; MEF2D/DAZAP1 fusion; Myocyte-specific enhancer factor 2D
基因别名: C80750; MEF2D
UniProt ID: (Human) Q14814, (Rat) O89038, (Mouse) Q63943
Entrez Gene ID: (Human) 4209, (Rat) 81518, (Mouse) 17261