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Proteintech

Phospho-TDP43 (Ser409, Ser410) Polyclonal Antibody

92 篇参考文献

查看其他33个TDP-43抗体

说明书

实验方案

技术支持

货号 22309-1-AP

此产品在中国无法购买

100 µL

说明书

实验方案

技术支持

抗体检测数据 (6)

Application

Phospho-TDP43 (Ser409, Ser410) Antibody in Western Blot (WB)

图: 1 / 6

Phospho-TDP43 (Ser409, Ser410) Antibody (22309-1-AP) in WB

Non-treated and Calyculin A treated HeLa cells were subjected to SDS PAGE followed by western blot with (Product # 22309-1-AP) (Phospho-TDP43 (Ser409/410) antibody) at dilution of 1:1,000 incubated at room temperature for 1 hours.

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产品信息

22309-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:300-1:1,000

查看30篇已发表文章 30篇已发表文章

免疫组化 (IHC)

Assay-dependent

查看34篇已发表文章 34篇已发表文章

免疫细胞化学 (ICC/IF)

查看24篇已发表文章 24篇已发表文章

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

不适用 (N/A)

查看3篇已发表文章 3篇已发表文章

产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide

偶联物

Unconjugated

形式

Liquid

浓度

See datasheet

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

22309-1-AP is a rabbit polyclonal antibody recognizing TDP-43 only when phosphorylated at 409/410. Immunohistochemical analyses using this antibody only stain the insoluble inclusions in pathologic tissues without normal diffuse nuclear staining.

靶标信息

TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

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Endogenous retroviruses and TDP-43 proteinopathy form a sustaining feedback driving intercellular spread of Drosophila neurodegeneration.

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Looking for answers far away from the soma-the (un)known axonal functions of TDP-43, and their contribution to early NMJ disruption in ALS.

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Looking for answers far away from the soma-the (un)known axonal functions of TDP-43, and their contribution to early NMJ disruption in ALS.

Molecular neurodegeneration

Ionescu A,Altman T,Perlson E

Wed May 31 00:00:00 UTC 2023

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TDP-43 and tau concurrence in the entorhinal subfields in primary age-related tauopathy and preclinical Alzheimer's disease.

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Sat Jul 01 00:00:00 UTC 2023

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Fri Apr 14 00:00:00 UTC 2023

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Thu Feb 02 00:00:00 UTC 2023

Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP.

Brain pathology (Zurich, Switzerland)

Cooper-Knock J,Julian TH,Feneberg E,Highley JR,Sidra M,Turner MR,Talbot K,Ansorge O,Allen SP,Moll T,Shelkovnikova T,Castelli L,Hautbergue GM,Hewitt C,Kirby J,Wharton SB,Mead RJ,Shaw PJ

Sun Jan 01 00:00:00 UTC 2023

Neuropathology of spinocerebellar ataxia type 8: Common features and unique tauopathy.

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Sun Oct 01 00:00:00 UTC 2023

Therapeutic Effect of Rapamycin on TDP-43-Related Pathogenesis in Ischemic Stroke.

International journal of molecular sciences

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Fri Dec 30 00:00:00 UTC 2022

TDP-43 Pathology and Prionic Behavior in Human Cellular Models of Alzheimer's Disease Patients.

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Sat Feb 05 00:00:00 UTC 2022

TDP-43 Pathology and Prionic Behavior in Human Cellular Models of Alzheimer's Disease Patients.

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Sat Feb 05 00:00:00 UTC 2022

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Saveri P,Magri S,Maderna E,Balistreri F,Lombardi R,Ciano C,Moda F,Garavaglia B,Reale C,Lauria Pinter G,Taroni F,Pareyson D,Pisciotta C

Fri Jul 01 00:00:00 UTC 2022

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Scientific reports

Pandit K,Petrescu J,Cuevas M,Stephenson W,Smibert P,Phatnani H,Maniatis S

Thu Mar 24 00:00:00 UTC 2022

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.

Nature neuroscience

Xie M,Liu YU,Zhao S,Zhang L,Bosco DB,Pang YP,Zhong J,Sheth U,Martens YA,Zhao N,Liu CC,Zhuang Y,Wang L,Dickson DW,Mattson MP,Bu G,Wu LJ

Sat Jan 01 00:00:00 UTC 2022

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.

Nature neuroscience

Xie M,Liu YU,Zhao S,Zhang L,Bosco DB,Pang YP,Zhong J,Sheth U,Martens YA,Zhao N,Liu CC,Zhuang Y,Wang L,Dickson DW,Mattson MP,Bu G,Wu LJ

Sat Jan 01 00:00:00 UTC 2022

Apolipoprotein L1 is increased in frontotemporal lobar degeneration post-mortem brain but not in ante-mortem cerebrospinal fluid.

Neurobiology of disease

Hok-A-Hin YS,Dijkstra AA,Rábano A,Hoozemans JJ,Castillo L,Seelaar H,van Swieten JC,Pijnenburg YAL,Teunissen CE,Del Campo M

Sat Oct 01 00:00:00 UTC 2022

TDP-43 Accumulation Within Intramuscular Nerve Bundles of Patients With Amyotrophic Lateral Sclerosis.

JAMA neurology

Kurashige T,Morino H,Murao T,Izumi Y,Sugiura T,Kuraoka K,Kawakami H,Torii T,Maruyama H

Fri Jul 01 00:00:00 UTC 2022

TDP-43 Accumulation Within Intramuscular Nerve Bundles of Patients With Amyotrophic Lateral Sclerosis.

JAMA neurology

Kurashige T,Morino H,Murao T,Izumi Y,Sugiura T,Kuraoka K,Kawakami H,Torii T,Maruyama H

Fri Jul 01 00:00:00 UTC 2022

An autopsy case of Alzheimer's disease with amygdala-predominant Lewy pathology presenting with frontotemporal dementia-like psychiatric symptoms.

Neuropathology : official journal of the Japanese Society of Neuropathology

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Fri Apr 01 00:00:00 UTC 2022

Amyotrophic lateral sclerosis with speech apraxia, predominant upper motor neuron signs, and prominent iron accumulation in the frontal operculum and precentral gyrus.

Neuropathology : official journal of the Japanese Society of Neuropathology

Mitani TT,Beck G,Kido K,Yamashita R,Yonenobu Y,Ogawa T,Saeki C,Okuno T,Nagano S,Morii E,Hasegawa M,Saito Y,Murayama S,Mochizuki H

Sun Aug 01 00:00:00 UTC 2021

Neuroinflammation is highest in areas of disease progression in semantic dementia.

Brain : a journal of neurology

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Tue Jun 22 00:00:00 UTC 2021

Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord.

Journal of neuropathology and experimental neurology

Cathcart SJ,Appel SH,Peterson LE,Greene EP,Powell SZ,Arumanayagam AS,Rivera AL,Cykowski MD

Fri Sep 10 00:00:00 UTC 2021

Repetitive Traumatic Brain Injury Is Associated With TDP-43 Alterations, Neurodegeneration, and Glial Activation in Mice.

Journal of neuropathology and experimental neurology

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Fri Jan 01 00:00:00 UTC 2021

Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Journal of neurochemistry

Vaca G,Martinez-Gonzalez L,Fernandez A,Rojas-Prats E,Porras G,Cuevas EP,Gil C,Martinez A,Martin-Requero Á

Mon Feb 01 00:00:00 UTC 2021

Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature.

Acta neuropathologica communications

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Tue Jun 29 00:00:00 UTC 2021

CdSe Quantum Dots in Human Models Derived from ALS Patients: Characterization, Nuclear Penetration Studies and Multiplexing.

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Tue Mar 09 00:00:00 UTC 2021

Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice.

Acta neuropathologica communications

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Mon Jan 18 00:00:00 UTC 2021

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Rojas-Prats E,Tosat-Bitrián C,Martínez-González L,Nozal V,Pérez DI,Martínez A

Thu Jan 28 00:00:00 UTC 2021

Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43^G298S transgenic mice.

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Sieverding K,Ulmer J,Bruno C,Satoh T,Tsao W,Freischmidt A,Akira S,Wong PC,Ludolph AC,Danzer KM,Lobsiger CS,Brenner D,Weishaupt JH

Fri Jan 01 00:00:00 UTC 2021

Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43^G298S transgenic mice.

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Fri Jan 01 00:00:00 UTC 2021

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Chatterjee A,Hirsch-Reinshagen V,Moussavi SA,Ducharme B,Mackenzie IR,Hsiung GR

Sat Apr 23 00:00:00 UTC 2022

Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.

Nature communications

Altman T,Ionescu A,Ibraheem A,Priesmann D,Gradus-Pery T,Farberov L,Alexandra G,Shelestovich N,Dafinca R,Shomron N,Rage F,Talbot K,Ward ME,Dori A,Krüger M,Perlson E

Thu Nov 25 00:00:00 UTC 2021

Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.

Nature communications

Altman T,Ionescu A,Ibraheem A,Priesmann D,Gradus-Pery T,Farberov L,Alexandra G,Shelestovich N,Dafinca R,Shomron N,Rage F,Talbot K,Ward ME,Dori A,Krüger M,Perlson E

Thu Nov 25 00:00:00 UTC 2021

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Thu Jul 01 00:00:00 UTC 2021

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Fri Aug 20 00:00:00 UTC 2021

Spinal Cord and Motor Neuron TDP-43 Pathology in a Sporadic Inclusion Body Myositis Patient.

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Thu Oct 15 00:00:00 UTC 2020

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Calpain-2 as a therapeutic target in repeated concussion-induced neuropathy and behavioral impairment.

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Wed Jul 01 00:00:00 UTC 2020

Use of Capillary Electrophoresis Immunoassay to Search for Potential Biomarkers of Amyotrophic Lateral Sclerosis in Human Platelets.

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Mon Feb 10 00:00:00 UTC 2020

Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS.

Journal of neurology, neurosurgery, and psychiatry

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Sat Feb 01 00:00:00 UTC 2020

A clinicopathological study of ALS with L126S mutation in the SOD1 gene presenting with isolated inferior olivary hypertrophy.

Neuropathology : official journal of the Japanese Society of Neuropathology

Hideshima M,Beck G,Yamadera M,Motoyama Y,Ikenaka K,Kakuda K,Tsuda H,Nagano S,Fujimura H,Morii E,Murayama S,Mochizuki H

Wed Apr 01 00:00:00 UTC 2020

Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation.

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Fri Sep 25 00:00:00 UTC 2020

A robust TDP-43 knock-in mouse model of ALS.

Acta neuropathologica communications

Huang SL,Wu LS,Lee M,Chang CW,Cheng WC,Fang YS,Chen YR,Cheng PL,Shen CJ

Tue Jan 21 00:00:00 UTC 2020

A robust TDP-43 knock-in mouse model of ALS.

Acta neuropathologica communications

Huang SL,Wu LS,Lee M,Chang CW,Cheng WC,Fang YS,Chen YR,Cheng PL,Shen CJ

Tue Jan 21 00:00:00 UTC 2020

Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain.

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Gregory JM,Livesey MR,McDade K,Selvaraj BT,Barton SK,Chandran S,Smith C

Wed Jan 01 00:00:00 UTC 2020

Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis.

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Gregory JM,Elliott E,McDade K,Bak T,Pal S,Chandran S,Abrahams S,Smith C

Wed Apr 01 00:00:00 UTC 2020

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Sun Nov 01 00:00:00 UTC 2020

Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.

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Posa D,Martínez-González L,Bartolomé F,Nagaraj S,Porras G,Martínez A,Martín-Requero Á

Mon Apr 01 00:00:00 UTC 2019

Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.

Molecular neurobiology

Posa D,Martínez-González L,Bartolomé F,Nagaraj S,Porras G,Martínez A,Martín-Requero Á

Mon Apr 01 00:00:00 UTC 2019

Phospho-Tau Changes in the Human CA1 During Alzheimer's Disease Progression.

Journal of Alzheimer's disease : JAD

Regalado-Reyes M,Furcila D,Hernández F,Ávila J,DeFelipe J,León-Espinosa G

Wed Sep 09 00:00:00 UTC 2020

Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial.

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Statland JM,Moore D,Wang Y,Walsh M,Mozaffar T,Elman L,Nations SP,Mitsumoto H,Fernandes JA,Saperstein D,Hayat G,Herbelin L,Karam C,Katz J,Wilkins HM,Agbas A,Swerdlow RH,Santella RM,Dimachkie MM,Barohn RJ

Fri Feb 01 00:00:00 UTC 2019

Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial.

Muscle & nerve

Fri Feb 01 00:00:00 UTC 2019

Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation.

The Journal of biological chemistry

Chen Y,Cohen TJ

Fri Mar 08 00:00:00 UTC 2019

Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation.

The Journal of biological chemistry

Chen Y,Cohen TJ

Fri Mar 08 00:00:00 UTC 2019

Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation.

The Journal of biological chemistry

Chen Y,Cohen TJ

Fri Mar 08 00:00:00 UTC 2019

Aggregation of the nucleic acid-binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation.

The Journal of biological chemistry

Chen Y,Cohen TJ

Fri Mar 08 00:00:00 UTC 2019

Association between TDP-43 and mitochondria in inclusion body myositis.

Laboratory investigation; a journal of technical methods and pathology

Huntley ML,Gao J,Termsarasab P,Wang L,Zeng S,Thammongkolchai T,Liu Y,Cohen ML,Wang X

Mon Jul 01 00:00:00 UTC 2019

Association between TDP-43 and mitochondria in inclusion body myositis.

Laboratory investigation; a journal of technical methods and pathology

Huntley ML,Gao J,Termsarasab P,Wang L,Zeng S,Thammongkolchai T,Liu Y,Cohen ML,Wang X

Mon Jul 01 00:00:00 UTC 2019

Association between TDP-43 and mitochondria in inclusion body myositis.

Laboratory investigation; a journal of technical methods and pathology

Huntley ML,Gao J,Termsarasab P,Wang L,Zeng S,Thammongkolchai T,Liu Y,Cohen ML,Wang X

Mon Jul 01 00:00:00 UTC 2019

Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis.

Biochemistry

Ng JSW,Hanspal MA,Matharu NS,Barros TP,Esbjörner EK,Wilson MR,Yerbury JJ,Dobson CM,Kumita JR

Tue Oct 01 00:00:00 UTC 2019

Variably protease-sensitive prionopathy mimicking frontotemporal dementia.

Neuropathology : official journal of the Japanese Society of Neuropathology

Aizpurua M,Selvackadunco S,Yull H,Kipps CM,Ironside JW,Bodi I

Mon Apr 01 00:00:00 UTC 2019

Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.

Acta neuropathologica communications

Sacino AN,Prokop S,Walsh MA,Adamson J,Subramony SH,Krans A,Todd PK,Giasson BI,Yachnis AT

Wed Oct 30 00:00:00 UTC 2019

Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis.

Acta neuropathologica

Henstridge CM,Sideris DI,Carroll E,Rotariu S,Salomonsson S,Tzioras M,McKenzie CA,Smith C,von Arnim CAF,Ludolph AC,Lulé D,Leighton D,Warner J,Cleary E,Newton J,Swingler R,Chandran S,Gillingwater TH,Abrahams S,Spires-Jones TL

Thu Feb 01 00:00:00 UTC 2018

Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis.

Acta neuropathologica

Thu Feb 01 00:00:00 UTC 2018

Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis.

Acta neuropathologica communications

Cykowski MD,Powell SZ,Appel JW,Arumanayagam AS,Rivera AL,Appel SH

Fri Apr 13 00:00:00 UTC 2018

Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis.

Acta neuropathologica communications

Cykowski MD,Powell SZ,Appel JW,Arumanayagam AS,Rivera AL,Appel SH

Fri Apr 13 00:00:00 UTC 2018

Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis.

Acta neuropathologica communications

Cykowski MD,Powell SZ,Appel JW,Arumanayagam AS,Rivera AL,Appel SH

Fri Apr 13 00:00:00 UTC 2018

Reappraisal of TDP-43 pathology in FTLD-U subtypes.

Acta neuropathologica

Mackenzie IR,Neumann M

Sat Jul 01 00:00:00 UTC 2017

Reappraisal of TDP-43 pathology in FTLD-U subtypes.

Acta neuropathologica

Mackenzie IR,Neumann M

Sat Jul 01 00:00:00 UTC 2017

Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis.

Journal of neuropathology and experimental neurology

Cykowski MD,Powell SZ,Peterson LE,Appel JW,Rivera AL,Takei H,Chang E,Appel SH

Mon May 01 00:00:00 UTC 2017

Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis.

Journal of neuropathology and experimental neurology

Cykowski MD,Powell SZ,Peterson LE,Appel JW,Rivera AL,Takei H,Chang E,Appel SH

Mon May 01 00:00:00 UTC 2017

Platelet phosphorylated TDP-43: an exploratory study for a peripheral surrogate biomarker development for Alzheimer's disease.

Future science OA

Wilhite R,Sage JM,Bouzid A,Primavera T,Agbas A

Wed Nov 01 00:00:00 UTC 2017

Platelet phosphorylated TDP-43: an exploratory study for a peripheral surrogate biomarker development for Alzheimer's disease.

Future science OA

Wilhite R,Sage JM,Bouzid A,Primavera T,Agbas A

Wed Nov 01 00:00:00 UTC 2017

In vitro prion-like behaviour of TDP-43 in ALS.

Neurobiology of disease

Smethurst P,Newcombe J,Troakes C,Simone R,Chen YR,Patani R,Sidle K

Thu Dec 01 00:00:00 UTC 2016

In vitro prion-like behaviour of TDP-43 in ALS.

Neurobiology of disease

Smethurst P,Newcombe J,Troakes C,Simone R,Chen YR,Patani R,Sidle K

Thu Dec 01 00:00:00 UTC 2016

In vitro prion-like behaviour of TDP-43 in ALS.

Neurobiology of disease

Smethurst P,Newcombe J,Troakes C,Simone R,Chen YR,Patani R,Sidle K

Thu Dec 01 00:00:00 UTC 2016

In vitro prion-like behaviour of TDP-43 in ALS.

Neurobiology of disease

Smethurst P,Newcombe J,Troakes C,Simone R,Chen YR,Patani R,Sidle K

Thu Dec 01 00:00:00 UTC 2016

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.

Nature medicine

Wang W,Wang L,Lu J,Siedlak SL,Fujioka H,Liang J,Jiang S,Ma X,Jiang Z,da Rocha EL,Sheng M,Choi H,Lerou PH,Li H,Wang X

Mon Aug 01 00:00:00 UTC 2016

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.

Nature medicine

Wang W,Wang L,Lu J,Siedlak SL,Fujioka H,Liang J,Jiang S,Ma X,Jiang Z,da Rocha EL,Sheng M,Choi H,Lerou PH,Li H,Wang X

Mon Aug 01 00:00:00 UTC 2016

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.

Nature medicine

Wang W,Wang L,Lu J,Siedlak SL,Fujioka H,Liang J,Jiang S,Ma X,Jiang Z,da Rocha EL,Sheng M,Choi H,Lerou PH,Li H,Wang X

Mon Aug 01 00:00:00 UTC 2016

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.

Nature medicine

Wang W,Wang L,Lu J,Siedlak SL,Fujioka H,Liang J,Jiang S,Ma X,Jiang Z,da Rocha EL,Sheng M,Choi H,Lerou PH,Li H,Wang X

Mon Aug 01 00:00:00 UTC 2016

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.

Nature medicine

Wang W,Wang L,Lu J,Siedlak SL,Fujioka H,Liang J,Jiang S,Ma X,Jiang Z,da Rocha EL,Sheng M,Choi H,Lerou PH,Li H,Wang X

Mon Aug 01 00:00:00 UTC 2016

The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity.

Nature medicine

Wang W,Wang L,Lu J,Siedlak SL,Fujioka H,Liang J,Jiang S,Ma X,Jiang Z,da Rocha EL,Sheng M,Choi H,Lerou PH,Li H,Wang X

Mon Aug 01 00:00:00 UTC 2016

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Molecular neurodegeneration

Alquezar C,Salado IG,de la Encarnación A,Pérez DI,Moreno F,Gil C,de Munain AL,Martínez A,Martín-Requero Á

Sat Apr 30 00:00:00 UTC 2016

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Molecular neurodegeneration

Alquezar C,Salado IG,de la Encarnación A,Pérez DI,Moreno F,Gil C,de Munain AL,Martínez A,Martín-Requero Á

Sat Apr 30 00:00:00 UTC 2016

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Molecular neurodegeneration

Alquezar C,Salado IG,de la Encarnación A,Pérez DI,Moreno F,Gil C,de Munain AL,Martínez A,Martín-Requero Á

Sat Apr 30 00:00:00 UTC 2016

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Molecular neurodegeneration

Alquezar C,Salado IG,de la Encarnación A,Pérez DI,Moreno F,Gil C,de Munain AL,Martínez A,Martín-Requero Á

Sat Apr 30 00:00:00 UTC 2016

PABPN1 suppresses TDP-43 toxicity in ALS disease models.

Human molecular genetics

Chou CC,Alexeeva OM,Yamada S,Pribadi A,Zhang Y,Mo B,Williams KR,Zarnescu DC,Rossoll W

Tue Sep 15 00:00:00 UTC 2015

PABPN1 suppresses TDP-43 toxicity in ALS disease models.

Human molecular genetics

Chou CC,Alexeeva OM,Yamada S,Pribadi A,Zhang Y,Mo B,Williams KR,Zarnescu DC,Rossoll W

Tue Sep 15 00:00:00 UTC 2015

An autopsy case of familial amyotrophic lateral sclerosis with a TARDBP Q343R mutation.

Neuropathology : official journal of the Japanese Society of Neuropathology

Okamoto K,Fujita Y,Hoshino E,Tamura Y,Fukuda T,Hasegawa M,Takatama M

Thu Oct 01 00:00:00 UTC 2015

An autopsy case of familial amyotrophic lateral sclerosis with a TARDBP Q343R mutation.

Neuropathology : official journal of the Japanese Society of Neuropathology

Okamoto K,Fujita Y,Hoshino E,Tamura Y,Fukuda T,Hasegawa M,Takatama M

Thu Oct 01 00:00:00 UTC 2015

An autopsy case of familial amyotrophic lateral sclerosis with a TARDBP Q343R mutation.

Neuropathology : official journal of the Japanese Society of Neuropathology

Okamoto K,Fujita Y,Hoshino E,Tamura Y,Fukuda T,Hasegawa M,Takatama M

Thu Oct 01 00:00:00 UTC 2015

An autopsy case of familial amyotrophic lateral sclerosis with a TARDBP Q343R mutation.

Neuropathology : official journal of the Japanese Society of Neuropathology

Okamoto K,Fujita Y,Hoshino E,Tamura Y,Fukuda T,Hasegawa M,Takatama M

Thu Oct 01 00:00:00 UTC 2015

ALS-FUS pathology revisited: singleton FUS mutations and an unusual case with both a FUS and TARDBP mutation.

Acta neuropathologica communications

King A,Troakes C,Smith B,Nolan M,Curran O,Vance C,Shaw CE,Al-Sarraj S

Fri Oct 09 00:00:00 UTC 2015

Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration.

Neuropathology and applied neurobiology

Bit-Ivan EN,Lee KH,Gitelman D,Weintraub S,Mesulam M,Rademakers R,Isaacs AM,Hatanpaa KJ,White CL,Mao Q,Akman O,DiMauro S,Bigio EH

Wed Oct 01 00:00:00 UTC 2014

Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: genetic, clinical and neuropathological analysis.

Acta neuropathologica

Dobson-Stone C,Luty AA,Thompson EM,Blumbergs P,Brooks WS,Short CL,Field CD,Panegyres PK,Hecker J,Solski JA,Blair IP,Fullerton JM,Halliday GM,Schofield PR,Kwok JB

Mon Apr 01 00:00:00 UTC 2013

Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: genetic, clinical and neuropathological analysis.

Acta neuropathologica

Dobson-Stone C,Luty AA,Thompson EM,Blumbergs P,Brooks WS,Short CL,Field CD,Panegyres PK,Hecker J,Solski JA,Blair IP,Fullerton JM,Halliday GM,Schofield PR,Kwok JB