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OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: D-OR-1; delta 1 opioid receptor; delta opioid receptor 1; Delta-type opioid receptor; DOR-1; K56; MSL-2; Opioid receptor; Opioid receptor A; opioid receptor, delta 1
基因别名: DOR; DOR-1; mDOR; Nbor; OPRD; OPRD1; Ror-a
UniProt ID: (Human) P41143, (Mouse) P32300, (Rat) P33533
Entrez Gene ID: (Human) 4985, (Mouse) 18386, (Rat) 24613