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NeoBiotechnologies
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Monoclonal Antibody (PODXL/2184)
产品信息
5420-MSM4-P0
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
PODXL/2184
抗原
Recombinant fragment of human Podocalyxin (around aa 310-447).
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GCTM-2 antigen; Gp200; MGC138240; PC; PCLP antibody; PCLP1 antibody; PODLX2; Podocalyxin; podocalyxin-like; Podocalyxin-like protein 1; podolyxin
基因别名: Gp200; PC; PCLP; PCLP-1; PCLP1; PODXL
UniProt ID: (Human) O00592
Entrez Gene ID: (Human) 5420
cell adhesion
negative regulation of cell adhesion
cell migration
negative regulation of cell-cell adhesion
positive regulation of cell migration
regulation of microvillus assembly
positive regulation of cell-cell adhesion mediated by integrin
leukocyte migration
glomerular visceral epithelial cell development
epithelial tube formation
